Drug Study Naproxen (Aleve)
Brand Names: Aleve, Anaprox, AnaproxDS, Apo-Napro-Na, Apo-Napro-NaDS, Apo-Naproxen, EC-Naprosyn, Naprelan, Napron X, Naprosyn, Naprosyn-E, Naprosyn-SR, Naxen, Novo-Naprox, Novo-Naprox Sodium DS, NuNaprox, Synflex, SynflexDS
Classifications: Therapeutic: nonopioid analgesics, nonsteroidal anti-inflammatory agents, antipyretics Inflammatory disorders, including: Rheumatoid arthritis (adults and children), Osteoarthritis.
Mechanism of Action
Inhibits prostaglandin synthesis. Therapeutic Effects: Decreased pain. Reduction of fever. Suppression of inflammation.
Contraindications/Precautions
Contraindicated in: Hypersensitivity; Crosssensitivity may occur with other NSAIDs, including aspirin; Active GI bleeding; Ulcer disease; Lactation: Passes into breast milk and should not be used by nursing mothers. Use Cautiously in: Severe cardiovascular, renal, or hepatic disease; History of ulcer disease or any other history of gastrointestinal bleeding (may increase the risk of GI bleeding); Underlying cardiovascular disease (may increase the risk of MI or stroke); Chronic alcohol use/abuse; Geri: Increased risk of adverse reactions; OB:
Avoid using during third trimester of pregnancy; may cause premature closure of the ductus arteriosis; Pedi: Children <2 yr (safety not established).
Adverse Reactions/Side Effects
CNS: dizziness, drowsiness, headache. EENT: tinnitus, visual disturbances. Resp: dyspnea. CV: edema, palpitations, tachycardia. GI: DRUG-INDUCED HEPATITIS, GI BLEEDING, constipation, dyspepsia, nausea, anorexia, diarrhea, discomfort, flatulence, vomiting. GU: cystitis, hematuria, renal failure. Derm: photosensitivity, rashes, sweating, pseudoporphyria (12% incidence in children with juvenile rheumatoid arthritis—discontinue therapy if this occurs). Hemat: blood dyscrasias, prolonged bleeding time. Misc: allergic reactions including ANAPHYLAXIS and STEVENS-JOHNSON SYNDROME.
Route/Dosage (Anti-inflammatory/Analgesic/Antidysmenorrheal)
PO (Adults): Naproxen—250–500 mg bid (up to 1.5 g/day). Delayed-release naproxen—375–500 mg twice daily. Naproxen sodium—275–550 mg twice daily (up to 1.65 g/day). PO (Children >2 yr): Analgesia: 5–7mg/kg/dose every 8–12 hr. Inflammatory disease: 10–15mg/kg/day divided q 12 hr,maximum: 1000mg/day.
Nursing Management
1. Advise patient to take this medication with a full glass of water and to remain in an upright position for 15–30min after administration.
2. Instruct patient to take medication as directed. Takemissed doses as soon as remembered but not if almost time for the next dose. Do not double doses.
3. May cause drowsiness or dizziness. Advise patient to avoid driving or other activities requiring alertness until response to the medication is known.
4. Caution patient to avoid the concurrent use of alcohol, aspirin, acetaminophen, or other OTCmedications without consulting health care professional. Use of naproxen with 3 or more glasses of alcohol per day may increase risk of GI bleeding.
5. Advise patient to inform health care professional of medication regimen prior to treatment or surgery.
6. Caution patient to wear sunscreen and protective clothing to prevent photosensitivity reactions (especially in children with juvenile rhumatoid arthritis [JRA]).
7. Instruct patients not to take OTC naproxen preparations for more than 3 days for fever and to consult health care professional if symptoms persist or worsen.
8. Advise patient to consult health care professional if rash, itching, visual disturbances, tinnitus, weight gain, edema, black stools, persistent headache, or influenza-like syndrome (chills, fever, muscle aches, pain) occurs.
Classifications: Therapeutic: nonopioid analgesics, nonsteroidal anti-inflammatory agents, antipyretics Inflammatory disorders, including: Rheumatoid arthritis (adults and children), Osteoarthritis.
Mechanism of Action
Inhibits prostaglandin synthesis. Therapeutic Effects: Decreased pain. Reduction of fever. Suppression of inflammation.
Contraindications/Precautions
Contraindicated in: Hypersensitivity; Crosssensitivity may occur with other NSAIDs, including aspirin; Active GI bleeding; Ulcer disease; Lactation: Passes into breast milk and should not be used by nursing mothers. Use Cautiously in: Severe cardiovascular, renal, or hepatic disease; History of ulcer disease or any other history of gastrointestinal bleeding (may increase the risk of GI bleeding); Underlying cardiovascular disease (may increase the risk of MI or stroke); Chronic alcohol use/abuse; Geri: Increased risk of adverse reactions; OB:
Avoid using during third trimester of pregnancy; may cause premature closure of the ductus arteriosis; Pedi: Children <2 yr (safety not established).
CNS: dizziness, drowsiness, headache. EENT: tinnitus, visual disturbances. Resp: dyspnea. CV: edema, palpitations, tachycardia. GI: DRUG-INDUCED HEPATITIS, GI BLEEDING, constipation, dyspepsia, nausea, anorexia, diarrhea, discomfort, flatulence, vomiting. GU: cystitis, hematuria, renal failure. Derm: photosensitivity, rashes, sweating, pseudoporphyria (12% incidence in children with juvenile rheumatoid arthritis—discontinue therapy if this occurs). Hemat: blood dyscrasias, prolonged bleeding time. Misc: allergic reactions including ANAPHYLAXIS and STEVENS-JOHNSON SYNDROME.
Route/Dosage (Anti-inflammatory/Analgesic/Antidysmenorrheal)
PO (Adults): Naproxen—250–500 mg bid (up to 1.5 g/day). Delayed-release naproxen—375–500 mg twice daily. Naproxen sodium—275–550 mg twice daily (up to 1.65 g/day). PO (Children >2 yr): Analgesia: 5–7mg/kg/dose every 8–12 hr. Inflammatory disease: 10–15mg/kg/day divided q 12 hr,maximum: 1000mg/day.
Nursing Management
1. Advise patient to take this medication with a full glass of water and to remain in an upright position for 15–30min after administration.
2. Instruct patient to take medication as directed. Takemissed doses as soon as remembered but not if almost time for the next dose. Do not double doses.
3. May cause drowsiness or dizziness. Advise patient to avoid driving or other activities requiring alertness until response to the medication is known.
4. Caution patient to avoid the concurrent use of alcohol, aspirin, acetaminophen, or other OTCmedications without consulting health care professional. Use of naproxen with 3 or more glasses of alcohol per day may increase risk of GI bleeding.
5. Advise patient to inform health care professional of medication regimen prior to treatment or surgery.
6. Caution patient to wear sunscreen and protective clothing to prevent photosensitivity reactions (especially in children with juvenile rhumatoid arthritis [JRA]).
7. Instruct patients not to take OTC naproxen preparations for more than 3 days for fever and to consult health care professional if symptoms persist or worsen.
8. Advise patient to consult health care professional if rash, itching, visual disturbances, tinnitus, weight gain, edema, black stools, persistent headache, or influenza-like syndrome (chills, fever, muscle aches, pain) occurs.
Categories:
Drug Study
2 komentar:
We were exploring the possibility of licensing a brand to that company for different geographies where we are not present, www.adderallxronline.com/xanax/
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.
Posting Komentar